Process for the preparation of enantiomerically pure flavone derivatives for the treatment of proliferative diseases

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专利权人:

ピラマル エンタープライジーズ リミテッド

发明人:

シバクマール・ミーナクシ,マスカレンハス・マルコルム,サルデ・アンクシュ,ジャドハブ・プラモド クマール,シュクラ・マノジ,ジョシ・カルパナ,ラトス・マギー

申请号：

JP2009515971

公开号：

JP5498782B2

申请日:

2006.06.21

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

The present invention relates to an enantiomerically pure (+)-trans enantiomer of a compound represented by the following formula (I): wherein R1, R2, R3, R4 and R9 are as defined in the specification； enantiomerically pure intermediates thereof, to processes for the preparation of the enantiomerically pure compound and its intermediates, and to a pharmaceutical composition comprising the enantiomerically pure compound. The compound of formula (I) is useful for the treatment of diseases or disorders mediated by the inhibition of cyclin dependant kinase, such as cancer.

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中国工程科技知识中心

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