The Government of The United States of America; as represented by the Secretary; Department of Health and Human Services
发明人:
申请号：
EP09759125.9
公开号：
EP2297186B1
申请日:
2009.05.29
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Group C rotaviruses are a cause of acute gastroenteritis in children and adults that is distinct from group A RV. However, human group C rotaviruses cannot be grown in culture, resulting in a lack of tools for detection and treatment of GrpC RV disease. Consequently, the burden of GpC RV disease has not been clearly established. Isolated recombinant human rotavirus group C virus-like particles are provided according to embodiments of the present invention along with methods of their production and use in, inter alia, detection of Grp C RV infection, diagnostic assays and immunogenic compositions.
