A guide catheter assembly includes an outer guide catheter and an inner catheter slidably and rotatably disposed in the outer guide catheter. The outer guide catheter has a proximal portion and a distal portion formed into a preformed shape including a curved segment. The preformed shape includes a first arc, a second arc, a third arc, a fourth arc, and a generally straight terminal portion. The preformed shape is generally a J-shape, having a terminal portion generally parallel to the proximal portion, a generally closed arc or a generally open arc.
