An optical method for determining morphological parameters of a tissue lesion comprises: generating a reflectance image of the lesion using an optical transfer diagnosis device； and determining a lesion border, a size of the lesion, a histogram width that gives a measure of inhomogeneity of the reflectance image of the lesion, a relative moment of inertia of the lesion, a center distance representing a physical distance between a geometrical center of the lesion and a center of mass of absorptance, a fractal dimension of the lesion that describes the complexity of its border, an asphericity of the lesion, a relative border length of the lesion, and, optionally, a darkness of the lesion defined as an average value of the reflected intensity of the lesion.
