The present invention relates compounds of Formula (A), as well as their preparation and uses, and further relates pharmaceutical compositions comprising these compounds and their uses as modulators of dysfunctional glutamate transmission. The present invention also relates to uses of the compounds or pharmaceutical compositions in treating or preventing certain neurological and psychiatric disorders and diseases as well as cancer in humans.本發明係關於一種式(A)化合物，以及其製備及用途，且進一步關於包含該些化合物的醫藥組合物以及其作為谷氨酸傳遞功能失調之調節劑。本發明亦關於該化合物或醫藥組合物用於治療或預防人類之一些神經及精神病症與疾病以及癌症之用途。
