A. crystallographic form of acrylonitrile-5 - (4-methyl-2-oxopiprazin-1-il) - 1,2,3,4-tetrahydrodiphenyl ether-1-carbohydrate-1-carbohydrate and its solution (2 - (3-chloro-2-fluorinated-6 - (1h-tetrazol-1-il) acrylonitrile-5 - (4-methyl-2-oxopiprazine-1-il) - 1,2,3,4-tetrahydroisoquine-1-carboxamida) benzene ether and its solution; Including the pharmacological synthesis of this crystal form; and the method of treating thrombus disorder with this crystal form or pharmacological synthesisReferida a formas cristalinas de acido (S,E)-4-(2-(3-(3-cloro-2-fluoro-6-(1H-tetrazol-1-il) fenil) acriloil)-5-(4-metil-2-oxopiperazin-1-il)-1, 2, 3, 4-tetrahidroisoquinolina-1-carboxamida) benzoico y sus solvatos del mismo; procesos para la produccion de tales formas cristalinas; composiciones farmaceuticas que comprenden tales formas cristalinas; y metodos para tratar trastornos tromboembolicos con tales formas cristalinas o tales composiciones farmaceuticas