Apparatuses, methods, and compositions for administering vaporized caryophyllene compositions to a human subject in need thereof. The caryophyllene compositions can be administered via a handheld electronic device that vaporizes pure, essentially pure, or substantially pure caryophyllene (beta caryophyllene and/or alpha caryophyllene) in small doses for inhalation by a user. Some compositions do not include or contain additional constituents, carriers, or additives, and demonstrate beneficial physiological effects that are not seen when alpha caryophyllene or beta caryophyllene is administered orally or by injection.