MICHELS, ANDREAS,SCHEIDIG, ANDREAS,ELEND, CHRISTIAN,KRAPP, CLAUDIA,HORN, THOMAS
申请号：
CA3047868
公开号：
CA3047868A1
申请日:
2017.12.22
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to a protease variant which is at least 90% identical to the full length amino acid sequence of a Kumamolisin AS backbone as set forth in any of SEQ ID NOs 1 - 3, while maintaining proteolytic activity, or a fragment, fraction or shuffled variant thereof maintaining proteolytic activity, which protease variant demonstrates altered or improved stability compared to the Kumamolisin AS wildtype as set forth in SEQ ID NO 4, or the Kumamolisin AS backbone as set forth in any of SEQ ID NOs 1 - 3.
