The present invention relates to a composition comprising a phospholipid or a metabolic precursor or metabolite thereof, or a mixture thereof, for use in promoting, supporting or optimizing one or more of the following: (i) de novo myelination； (ii) brain structure； (iii) brain connectivity； (iv) intellectual potential； (v) cognitive potential； (vi) learning potential； and (vii) cognitive function in an offspring of a female subject, wherein said composition is for administration to the female subject.
