Roberto Rastelli;Angela Armanni;Roberto Bilzi;Daniela Cocconi;Rosella Musa
发明人:
Roberto Bilzi,Angela Armanni,Roberto Rastelli,Daniela Cocconi,Rosella Musa
申请号:
US10592701
公开号:
US08153104B2
申请日:
2005.03.16
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides a formulation to be administered as dry powder for inhalation suitable for efficacious delivery of low-dosage strength active ingredients to the low respiratory tract of patient. In particular, the invention provides a formulation comprising microparticles constituted of microparticles of a low-dosage strength active ingredient and microparticles of an excipient wherein the MMD of the microparticles is comprised between 2 and 15 micron, at least 10% of the microparticles has a mass diameter (MD) higher than 0.5 micron, and the process of preparation thereof.