PROCEDES EVOLUTIFS ET A HAUT RENDEMENT POUR LA PRODUCTION DE GRANDES QUANTITES DE VECTEUR VIRAL ADENO-ASSOCIE RECOMBINE (VAAR) ET VECTEURS VIRAUX ADENO-ASSOCIES RECOMBINES (VAAR)AINSI PRODUITS
QU, GUANG,WRIGHT, JOHN FRASER,OH, YOUNGHOON,WANG, YUHUAN,ZHANG, HAIBO,DUNCAN, LAURA
申请号：
CA3031095
公开号：
CA3031095A1
申请日:
2017.07.21
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Provided are methods for producing recombinant adeno-associated virus (rAAV) vector particles at high recovery or high titer. Also provided are methods that concentrate rAAV vectors to a high concentration, for example, up to 5E+13 (5x1013) vector genomes per milliliter (Vg/ml) with little if any rAAV aggregates.
