Method for producing a stable suspension of insoluble particulates

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专利权人:

オバン・エナジー・リミテッド

发明人:

カン，シーマ,パリク，インデュ,ローリー，ヘレン・シー,カン,シーマ,パリク,インデュ,ローリー,ヘレン・シー

申请号：

JP2000583499

公开号：

JP5296954B2

申请日:

1999.11.19

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

Sub-micron and micron-size stable particles of water-insoluble or poorly soluble drugs or other industrially useful insoluble compounds suspended in an aqueous medium containing at least one surface modifier are prepared by selecting the surface modifier or modifiers such that the hydrophile-lipophile balance (HLB) of the composition, defined as formula (I): is between 4 and 9. This provides a reliable HLB-based selection criteria for selecting the type and amount of surface modifiers used to obtain sub-micron size stable suspensions.

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中国工程科技知识中心

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http://www.ckcest.cn/home/