The present invention provides an intermediate layer composed of a composition containing the following (a), (b) and (c1) on the surface of an insertion member inserted into a living body, and a composition containing the following (a), (b) and (c2). It is related with the medical tube by which the lubricating layer which consists of sequentially laminated stacked； (a) 1 to 35% by weight of at least one of aromatic diisocyanates, aliphatic diisocyanates and alicyclic diisocyanates, (b) 1 to 35% by weight of trifunctional or higher polyols, (c1) polyalkylene glycols and / or monomes 30 to 98% by weight of oxypolyalkylene glycol, (c2) polyalkylene glycol (including those having a weight average molecular weight greater than that of polyalkylene glycol of (c1)) and / or monomethoxypolyalkylene glycol (weight average molecular weight 30-98 weight% of things (the thing larger than the monomethoxy polyalkylene glycol of this (c1) is included) (with respect to (c1) and (c2), each glycol is a diol).본 발명은 생체 내에 삽입되는 삽입 부재의 표면에, 하기 (a), (b), (c1)을 함유하는 조성물로 이루어지는 중간층과, 하기 (a), (b), (c2)를 함유하는 조성물로 이루어지는 윤활층이 순차 적층된 의료용 튜브에 관한 것이다； (a) 방향족 디이소시아네이트, 지방족 디이소시아네이트 및 지환족 디이소시아네이트 중 적어도 1종 1 내지 35중량％, (b) 3관능 이상의 폴리올 1 내지 35중량％, (c1) 폴리알킬렌글리콜 및/또는 모노메톡시폴리알킬렌글리콜 30 내지 98중량％, (c2) 폴리알킬렌글리콜(중량 평균 분자량이 (c1)의 폴리알킬렌글리콜보다도 큰 것이 포함됨) 및/또는 모노메톡시폴리알킬렌글리콜(중량 평균 분자량이 (c1)의 모노메톡시폴리알킬렌글리콜보다도 큰 것이 포함됨) 30 내지 98중량％(단, (c1), (c2)에 관하여, 각 글리콜은 디올임).
