The disclosure is directed to a drug delivery device comprising a housing retaining a primary drug delivery assembly and a secondary drug delivery assembly. The secondary drug delivery assembly comprises a secondary dose setting mechanism with a biasing member adapted to reset the secondary dose setting mechanism in a resetting movement. An actuator is movable relative to the housing and comprises a first engagement section configured to engage a second engagement section provided by an actuation collar such that an actuation movement of the actuator is transferred to the actuation collar. A setting element is movable between a first position and a second position and is connected to the secondary dose setting mechanism such that during the resetting movement of the secondary dose setting mechanism, the setting element is moved from the second position into the first position.