An endoluminal prosthesis is provided for restricting fluid flow in a lumen. The endoluminal prosthesis has a tubular graft having a flexible body with at least one stent coupled thereto. The endoluminal prosthesis also includes a prosthetic valve coupled to the inside the tubular graft. The prosthetic valve can be made of a synthetic or an organic material, such as an extracellular matrix, and can operate to limit fluid flow in one direction, but allow fluid flow in the other direction.
