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Anti-IL-3Ra antibody for use in treatment of blood tumor
专利权人:
Kyowa Hakko Kirin Co.; Ltd.
发明人:
Tawara, Tomonori,Takayanagi, Shinichiro,Inagaki, Yoshimasa
申请号:
AU2014227539
公开号:
AU2014227539A1
申请日:
2014.09.19
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2014227539A120141009.pdf#####ABSTRACT The present invention provides an antibody to human IL-3Rc chain, which does not inhibit IL-3 signaling and binds to B domain of the human IL-3RaX chain but 5 does not bind to C domain of the human IL-3Ra chain a composition for preventing or treating a blood tumor in which a cell expressing IL-3Rax is found in bone marrow or peripheral blood of a subject, which comprises the antibody to human IL-3RcL as an active ingredient and a method for treating a blood tumor in which a cell expressing IL3Rc is found in bone marrow or peripheral blood, which comprises administering, to a 10 subject, a composition comprising the IL-3Ra antibody as an active ingredient. 98
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