A medicine for lowering LDL cholesterol is provided. A medicine for lowering LDL cholesterol, the medicine comprising a combination of a statin and (S)-trans-{4-[({2-[({1-[3,5-bis(trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl) ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid, a salt thereof, or a solvate of the compound or the salt.
