Pere Ristol Debart,Maria Mercedes Faro Tomas,Juan Ignacio Jorquera Nieto
申请号：
US12349604
公开号：
US08354505B2
申请日:
2009.01.07
申请国别(地区):
US
年份:
2013
代理人:
摘要：
A concentrate of Von Willebrand Factor (VWF) or a complex of Factor VIII/VWF is prepared by creating a solution of VWF or a complex of Factor VIII/VWF containing VWF at a concentration of up to 12 IU VWF:RCo/ml and a VWF/Factor VIII ratio of 0.4 or more and nanofiltering that starting solution through a filter of pore size of 35 nanometers or smaller. The resulting VWF retains high molecular weight multimers.
