An orthopedic insole is provided with an insole having a bottom portion for facing a sole of a shoe; one or more orthopedic pads disposed on the bottom portion of the insole at one or more judiciously selected locations to provide different heights and/or different physical properties. An orthopedic shoe is also provided having an upper; a sole attached to the upper, and the removable insole within the shoe. An orthopedic insole is provided with an insole having a bottom portion for facing a sole of a shoe; a first orthopedic pad disposed on the bottom portion of the insole at a location corresponding to at least one selected from the group consisting of a medial longitudinal arch, a lateral longitudinal arch, and a transverse metatarsal arch of a foot.