תרכובות פירימידינ–2–אמין והשימוש בהן כמעקבים של קינאזות jak

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专利权人:

ANKUSH ARGADE;SOMASEKHAR BHAMIDIPATI;IHAB DARWISH;RAJINDER SINGH;JIAXIN YU;HUI HONG;SAMBIAH THOTA;VADIM MARKOVTOSOV;RIGEL PHARMACEUTICALS INC.;JEFFREY CLOUGH;PINGYU DING;ANDY ATUEGBU

发明人:

SOMASEKHAR BHAMIDIPATI,JEFFREY CLOUGH,ANKUSH ARGADE,RAJINDER SINGH,VADIM MARKOVTOSOV,PINGYU DING,JIAXIN YU,ANDY ATUEGBU,HUI HONG,IHAB DARWISH,SAMBIAH THOTA

申请号：

IL20760910

公开号：

IL207609A

申请日:

2010.08.12

申请国别(地区):

IL

年份:

2015

代理人:

摘要：

This invention is directed to compounds of formula (I): where n, m, Y, R1, R2, R3, R4 and R5 are disclosed herein, as isolated stereoisomers or mixtures thereof, or as pharmaceutically acceptable salts thereof； pharmaceutical compositions comprising the compounds of formula (I)； and methods of using the compounds and the pharmaceutical compositions in treating diseases or conditions associated with JAK2 activity.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/