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THERAPEUTIC COMBINATION COMPRISING A PLK1 INHIBITOR AND AN ANTINEOPLASTIC AGENT
专利权人:
Barbara Valsasina
发明人:
Barbara Valsasina,Italo Beria,Antonella Ciavolella,Dario Ballinari,Enrico Pesenti,Valter Domenico Croci,Mara Emanuela Casnaghi,Alessandro Luciano Croci,Juergen Moll
申请号:
US13321024
公开号:
US20120114641A1
申请日:
2010.05.21
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides a combination comprising (a) a compound of formula (I) and (b) one or more antineoplastic agents selected from the group consisting of an antimetabolite agent, analkylating or alkylating-like agent, an intercalating agent, a topoisomerase I or II inhibitor, an antimitotic agent, a kinase inhibitor, a proteasome inhibitor and an antibody inhibiting a growth factor or its receptor, wherein active ingredients of the combination are present in each case in free form or in the form of a pharmaceutically acceptable salt or any hydrate or solvate thereof, useful in the treatment of tumors.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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