Diamin-származékok mint leukotrién A4 hidroláz inhibitorok

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专利权人:

Inc.;Celtaxsys

发明人:

ARNAIZ, Damian,DAVEY, David,GUILFORD, William,CLEVE, Arwed,KIRKLAND, Thomas,CLARET, Emmanuel,KHIM, Seock-Kyu,BROWN, Greg,YE, Bin,LIGHT, David,LIANG, Amy,KOCHANNY, Monica,WEI, Guo, Ping,PARKINSON, John

申请号：

HUE06848156

公开号：

HUE031972T2

申请日:

2006.12.22

申请国别(地区):

HU

年份:

2017

代理人:

摘要：

This invention is directed to compounds of formula (I): where r, q, R, R 2 , R 3 , R 4 , R 5a , R 5b , R 5c , R 6a , R 6b , R 6c , R 7 , R 8 , and R 9 are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxides or prodrugs thereof； which are leukotriene A 4 hydrolase inhibitors and therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.

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