Disclosed are compounds of formula (I) Where Ar<；SUB>；1<；/SUB>；, X, Y, Q, W, R<；SUP>；3<；/SUP>；, R<；SUP>；4<；/SUP>；, R<；SUP>；5<；/SUP>；, R<；SUP>；6 <；/SUP>；and R<；SUP>；y <；/SUP>；are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. The compounds are also useful for treating diseases or conditions related to oncology and anticoagulant or fibrinolytic therapy. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.本發明揭示式(I)之化合物其中Ar1，X，Y，Q，W，R3，R4，R5，R6和Ry如本文中所定義。本發明之化合物係抑制與發炎過程有關之細胞素的產生，並因此可用於治療與發炎有關之疾病以及病理症狀，例如慢性發炎疾病。在此亦揭示製備該等化合物和包含該等化合物之醫藥組合物。
