SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH;ARAGON PHARMACEUTICALS, INC.
发明人:
SMITH, NICHOLAS D.,HERBERT, MARK R.,OUERFELLI, OUATHEK,DILHAS, ANNA
申请号：
PE2014002383
公开号：
PE20150631A1
申请日:
2013.06.04
申请国别(地区):
PE
年份:
2015
代理人:
摘要：
The invention describes the amoxic method and crystal form of androgenico 4 - [7 - (6-cyano-5-trifluorpyridine-3-il) - 8-oxo-6-tioxo-5, 7-diazespiro [3.4loct-5-il] - 2-fluoro-n-metallic benzamida] receiver module. In addition, appropriate pharmacological components for the management of mammals are described, including modules of the androgenico receiver, and methods of using the androgenico receiver module alone or in combination with other compounds to treat diseases or diseases related to the activity of the androgenico receiver.La invencion describe formas amorfas y cristalinas del modulador del receptor androgenico 4-[7-(6-ciano-5-trifluorometilpiridin-3-il)-8-oxo-6-tioxo-5,7- diazaspiro[3.4loct-5-il]-2-fluoro-N-metilbenzamida. Ademas, se describen composiciones farmaceuticas adecuadas para administrar a un mamifero que incluyen el modulador del receptor androgenico y metodos para usar el modulador del receptor androgenico, solo o en conjunto con otros compuestos, para tratar enfermedades o afecciones asociadas con la actividad del receptor androgenico
