Robert W. Clarke;David L. Hava;Michael M. Lipp;Richard Batycky;John Hanrahan
发明人:
Michael M. Lipp,Robert W. Clarke,David L. Hava,Richard Batycky,John Hanrahan
申请号:
US13259651
公开号:
US20120107414A1
申请日:
2010.03.26
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to pharmaceutical formulations for treating a respiratory tract infection or a pulmonary disease in an individual, comprising a calcium salt and a sodium salt, wherein the ratio of Ca+2 to Na+ is from about 4:1 (mole:mole) to about 16:1 (mole:mole). The invention also relates to methods of treating (including prophylactically treating) and reducing the spread of a respiratory tract infection, methods of treating (including prophylactically treating) a pulmonary disease or an acute exacerbation of a pulmonary disease, and methods of reducing the spread of an acute exacerbation of a pulmonary disease, comprising administering a pharmaceutical formulation that comprises a calcium salt and a sodium salt.