PROBLEM TO BE SOLVED: To provide a novel technique for cancer therapy.SOLUTION: A screening method for a cancer therapy agent effective in a cancer stem cell in vivo or in vitro comprises following processes: Process 1: a process of culturing an iPS cell under presence of a culture component comprised in a culture medium of a cancer cell to induce a cell population comprising a cancer stem cell. Process 2: a process of acting a candidate substance of a cancer therapy agent on the cell population comprising the cancer stem cell in vivo or in vitro to screening the cancer therapy agent effective in the cancer stem cell.COPYRIGHT: (C)2015,JPO&INPIT【課題】新しいがん治療の技術を提供する。【解決手段】以下の工程を含むことを特徴とする、in vivo又はin vitroでがん幹細胞に有効ながん治療薬をスクリーニングする方法:工程1:iPS細胞をがん細胞の培地に含まれる培養成分の存在下に培養して、がん幹細胞を含む細胞集団を誘導する工程、工程2:in vivo又はin vitroでがん幹細胞を含む細胞集団にがん治療薬の候補物質を作用させて、がん幹細胞に有効ながん治療薬をスクリーニングする工程【選択図】図16
