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TRANSDERMAL PATCH CONTAINING FENTANYL OR SALT THEREOF
专利权人:
发明人:
NAKAMURA NOBUKI,OGAWA TAKAYUKI,TSUJIMOTO YOSHIKAZU,IKEDA MASASHI
申请号:
IN436/DELNP/2011
公开号:
IN2011DN00436A
申请日:
2011.01.19
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
The purpose is to provide a patch containing Fentanyls in which the time-dependent deposition of the crystals of fentanyl is inhibited without decreasing the adhesiveness to the skin, and which has drug stability with low irritation to the skin and favorable permeability of fentanyl to the skin. A patch containing Fentanyls, comprising a support, an adhesive layer containing Fentanyls, and a release liner, wherein the adhesive layer containing Fentanyls contains 0.01-0.5% by mass of ascorbic acid ester such as L-ascorbic acid palmitate. In addition, a patch containing Fentanyls, which further contains a sufficient amount of hindered phenol-type anti-oxidant for inhibiting deposition of fentanyl or a salt thereof is provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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