Provided is a skin composition for external use that has skin barrier function-enhancing effects. This skin composition for external use comprises pentosan polysulphate and/or a salt thereof as an active ingredient. The skin composition for external use is useful for preventing and/or treating diseases selected from the group consisting of atopic dermatitis, psoriasis, asteatotic eczema, hand eczema, ichthyosis, and rosacea.本發明提供一種具有皮膚屏障功能改善作用之皮膚外用組成物。本發明之皮膚外用組成物含有戊聚醣多硫酸酯（pentosan polysulfate）及/或其鹽作為有效成分。該皮膚外用組成物有效用以預防及/或治療選自由異位性皮膚炎、牛皮癬、皮脂缺乏性濕疹、手濕疹、魚鱗癬、及酒渣所組成之群中之疾病。
