BALAJI BHARATWAJ,SAI PRASANTH CHAMARTHY,CHINEDU G. OREKIE,YOEN-JU SON
申请号：
US15104693
公开号：
US20160317391A1
申请日:
2014.12.12
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The invention disclosed herein is a novel media milling process performed in an atmosphere of propellants(s) utilizing a resonant acoustic mixing (RAM) device. The process is utilized to reduce the particle size of API (optionally including excipients) to a respirable size range while ensuring the retention of the crystallinity of the milled API.
