Jimenez Ana Isabel,Pañeda Covadonga,Martinez Tamara
申请号：
US201415030188
公开号：
US9951338(B2)
申请日:
2014.10.21
申请国别(地区):
美国
年份:
2018
代理人:
Brivanlou Margaret B.`King & Spalding LLP
摘要：
The invention relates to siRNA molecules and their use in methods and pharmaceutical compositions for inhibiting the expression of the PDK1 gene. The invention also relates to the use of said siRNAs molecules in the treatment and/or prevention of an eye condition characterized by increased expression and/or activity of PDK1 gene, preferably said eye condition is conjunctivitis and/or an ocular allergy such as seasonal allergic conjunctivitis, perennial allergic conjunctivitis, vernal keratoconjunctivitis, atopic keratoconjunctivitis, and giant papillary conjunctivitis.
