Stabilized SOS1 peptides

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专利权人:

DANA-FARBER CANCER INSTITUTE; INC.

发明人:

Elizaveta Leshchiner,Loren D. Walensky

申请号：

US14772136

公开号：

US10087215B2

申请日:

2014.03.14

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Provided herein are polypeptides containing stabilized therapeutic peptides related to KRAS guanidine exchange factor (SOS1). Also provided are compositions containing these polypeptides and methods of using such peptides in the treatment of cancer that includes administering to a subject one of the polypeptides. This disclosure relates to structurally stabilized therapeutic peptides related to KRAS guanidine exchange factor (SOS1), and methods of using such peptides in the treatment of cancer.

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