Patent No. 589755 Disclosed is an immunogenic composition for prophylaxis and treatment against any known serotype of human papillomavirus (HPV) and hepatitis B infection in humans, wherein the immunogenic composition consists of complete or partial, mutant or variant polypeptides or specific T or B cell epitopes of the capsid protein L1 HPV antigens either as single sequence or in tandem repeats in chimeric fusions with hepatitis B surface antigen (HbsAg).