您的位置: 首页 > 农业专利 > 详情页

CASTRATION RESISTANT PROSTATE CANCER
专利权人:
TARGIMMUNE THERAPEUTICS AG
发明人:
Esteban POMBO-VILLAR,Alexander LEVITZKI,Yael LANGUT,Maya ZIGLER,Alexei SHIR,Eric KITAS
申请号:
US16650980
公开号:
US20200230248A1
申请日:
2018.09.27
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to a polyplex for use in the treatment of castration resistant prostate cancer (CRPC) comprising a double stranded RNA (dsRNA) and a polymeric conjugate, wherein said polymeric conjugate consists of a linear polyethyleneimine (LPEl), one or more polyethylene glycol (PEG) moieties, one or more linkers and one or more targeting moieties, wherein said LPEl is covalently bound to one or more PEG moieties and each of said one or more PEG moieties is conjugated via one of the one or more linkers to one of the one or more targeting moieties, wherein each of said one or more targeting moieties is capable of binding to a cancer antigen, and wherein said cancer antigen is prostate surface membrane antigen (PSMA). Further, the invention relates to a pharmaceutical composition for use in the treatment of CRPC.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充