The invention relates to an electrophysiological analysis system comprising: a series of electrodes intended to be placed in different regions of the human body; a direct current voltage source; a control device adapted (i) to selectively apply direct current pulses, generated by the voltage source, to a pair of so-called active electrodes, said active electrodes forming an anode and a cathode, and (ii) to connect at least one other so-called passive electrode with high-impedance, said passive electrode(s) measuring the potential reached by the body; and a measurement device arranged to obtain data representative of the current at the cathode and the potentials on at least some of the electrodes connected with high impedance, in response to the application of the pulses, which data can be used to determine a value for the electrochemical conductance of the skin. The system is characterised in that the measurement device is adapted to determine simultaneously the values of the current at the anode and at the cathode and to deduce therefrom the values of the electrochemical conductance of the skin at the anode and the cathode.