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INFECTIVE DISEASE VIRUS, INFECTIOUS MV-DELTAC, METHOD FOR PREPARING CELLS, VACCINE PDCS, PHARMACEUTICAL COMPOSITION AND GROUPING OF ACTIVE INGREDIENTS
专利权人:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);INSTITUT PASTEUR;UNIVERSITE DE NANTES
发明人:
CHANTAL COMBREDET,FRÉDÉRIC TANGY,JEAN-BAPTISTE GUILLERME,JEAN-FRANÇOIS FONTENEAU,MARC GREGOIRE
申请号:
BR112015017692
公开号:
BR112015017692A2
申请日:
2014.01.20
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
infectious measles virus, infectious mv-del tac, method for preparing cells, vaccine pdcs, pharmaceutical composition and grouping of active ingredients. The invention relates to a genetically modified infectious measles virus derived from an attenuated live measles virus strain in which the gene encoding the viral accessory protein c has been deleted (mv-deltac). in particular, it relates to the use of said genetically modified infectious mv-delta in the treatment of malignant tumors or cancerous conditions, and for the preparation of agents or compositions for such treatment.vírus do sarampo infeccioso, mv-del tac infeccioso, método para preparar células, pdcs vacinais, composição farmacêutica e agrupamento de ingredientes ativos. a invenção refere-se a um vírus do sarampo infeccioso geneticamente modificado, derivado de uma linhagem de vírus do sarampo vivo atenuado, em que o gene que codifica a proteína c acessória viral foi eliminado (mv-deltac). em particular, refere-se ao uso do dito mv-delta c infeccioso geneticamente modificado no tratamento de tumores malignos ou de condições cancerosas, e para a preparação de agentes ou composições para esse tratamento.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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