A percutaneous endoscopic disc MR (mixed reality) glasses positioning device, characterized in that a control unit receives 3D scan data of a spine region of a patient through a communication interface, and then The 3D scan data described above is transmitted to the binocular lens unit via an image interface to generate a 3D spine virtual image, the 3D spine virtual image has an image of the intervertebral disc to be processed, and the control unit provides a Tracking and positioning function, so that the 3D spine virtual image can overlap with a 3D spine real image of the spine area to generate a 3D spine mixed augmented reality image, so that a surgical operator can use the 3D spine mixed augmented reality The reality image determines a straight path in the spine area to perform a reaming operation to form a guide channel connected to the intervertebral disc to be treated by a surface incision, and then performs the intervertebral disc to be processed through the guide channel An endoscopic surgery.一種經皮內視鏡椎間盤MR(mixed reality;混合實境)眼鏡定位裝置,其特徵在於:其一控制單元係藉由一通信介面接收一病患之一脊椎區域的3D掃描資料,再將所述的3D掃描資料經由一影像介面傳送至二目鏡單元以產生一3D脊椎虛擬影像,該3D脊椎虛擬影像具有一待處理的椎間盤之影像,且該控制單元係藉由所述二攝影單元提供一追蹤定位功能,以使該3D脊椎虛擬影像能和該脊椎區域之一3D脊椎現實影像重疊以產生一3D脊椎混合擴增實境影像,俾利一手術操作者能夠藉由該3D脊椎混合擴增實境影像在該脊椎區域中決定一直線路徑以進行一擴孔操作,以形成由一表面切口連接至該待處理的椎間盤之一導引通道,然後經由該導引通道對該待處理的椎間盤進行一內視鏡手術。