The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Fibroblast growth factor 21 (FGF21), in particular, by targeting natural antisense polynucleotides of Fibroblast growth factor 21 (FGF21). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of FGF21.本發明係關於調節纖維母細胞生長因子21(FGF21)之表現及/或功能之反義寡核苷酸，特定而言，藉由靶向纖維母細胞生長因子21(FGF21)之天然反義聚核苷酸來調節。本發明亦係關於該等反義寡核苷酸之鑑別及其在治療與FGF21表現有關之疾病及病症中的用途。
