David Charles Jackson,Weiguang Zeng,Brendon Yew Loong Chua
申请号：
US12682415
公开号：
US09089508B2
申请日:
2008.10.09
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to the targeted delivery of molecules to cells expressing toll-like receptors (TLRs). Aspects of the invention provide compounds comprising a positively charged group linked to a TLR ligand. These compounds are useful for in vitro and in vivo methods of transfection of TLR-expressing cells. Other aspects of the invention relate to the use of such compounds for repression of gene expression and DNA vaccination approaches.
