Peter Kufer,Tobias Raum,Markus Muenz,Jochen Pendzialek,Walter Fiers,Xavier Saelens,Kenny Roose
申请号:
US14774293
公开号:
US20160039948A1
申请日:
2014.03.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to an antibody construct comprising a first human binding domain specific for the extracellular part of the influenza envelope protein M2 (M2e) and a second domain specific for CD3. Moreover, the invention provides a nucleic acid molecule encoding the antibody construct, a vector comprising said nucleic acid molecule and a host cell transformed or transfected with said nucleic acid molecule or vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a pharmaceutical composition comprising said antibody construct, a medical use/method of treatment relating to said antibody construct, and a kit comprising said antibody construct.