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Automated nucleic acid repeat count calling methods
专利权人:
COUNSYL INC.
发明人:
申请号:
IL24559516
公开号:
IL245595D0
申请日:
2016.05.10
申请国别(地区):
IL
年份:
2016
代理人:
摘要:
The present disclosure relates to processes for determining the number of nucleic acid repeats in a DNA fragment comprising a nucleic acid repeat region. One example method may include receiving DNA size and abundance data generated by resolving DNA amplification products. A set of low-pass data may be generated by applying a low-pass filter to the DNA size and abundance data and a set of band-pass data may be generated by applying a band-pass filter to the DNA size and abundance data. A peak of the DNA size and abundance data representative of a number of nucleic acid repeats in the DNA may be identified based on peaks identified from the low-pass data and the band-pass data.
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