Institut Jean Paoli & Irène Calmettes;Université d'Aix-Marseille;UNIVERSITE CLAUDE BERNARD - LYON 1;Centre Leon Berard;INSERM (Institut National de la Santé et de la Recherche Médicale)
发明人:
申请号：
EP19185266.4
公开号：
EP3590969A1
申请日:
2012.03.29
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention provides antibodies directed against ICOS or a derivative thereof which induce IL-10 and IFNy production, induce CD4+ T cells proliferation, reduce Tconv proliferation, and increase the immunosuppressive function of Treg. The present invention also relates to uses of said antibodies for treating autoimmune diseases, transplantation rejection and graft versus host disease."
