Richard Heng;Rudolf Waelchli;Robert Alexander Pulz;Anna Vulpetti;Guido Koch;Elizabeth Kate Hoegenauer
发明人:
Richard Heng,Elizabeth Kate Hoegenauer,Guido Koch,Robert Alexander Pulz,Anna Vulpetti,Rudolf Waelchli
申请号:
US14130536
公开号:
US20140243306A1
申请日:
2012.07.07
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention describes new pyrrolo pyrimidine derivatives and pharmaceutically acceptable salts thereof which appear to interact with Bruton's tyrosine kinase (Btk). Accordingly, the novel pyrrolo pyrimidines may be effective in the treatment of autoimmune disorders, inflammatory diseases, allergic diseases, airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD), transplant rejection, cancers e.g. of hematopoietic origin or solid tumors.