A tablet packaging system and method is described. The illustrative tablet packaging system includes a plurality of pouches, a primary container, a sleeve, and a label. Each pouch of the plurality of pouches contains a plurality of tablets, and each pouch is detachably coupled to one another. The primary container includes a left side wall, a right side wall, a front side wall, a back side wall, and a bottom side wall that abut one another to form a cavity for receiving the plurality of pouches. The sleeve includes a top side wall, a bottom side wall, a right side wall, and a left side wall configured to receive the primary container. The label is affixed to the sleeve and includes at least one item from a list including: a patient name, a patient tablet, a prescribing physician name, a warning, and a bar code.