您的位置：
首页
>
农业专利
>
详情页
Inhibidores de GLyT1 para su uso en el tratamiento de trastornos hemáticos
- 专利权人:
- F. Hoffmann-La Roche AG
- 发明人:
- ALBERATI, Daniela,KOERNER, Annette,PINARD, Emmanuel,WINTER, Michael
- 申请号：
- ES15717916
- 公开号：
- ES2683184T3
- 申请日:
- 2015.04.27
- 申请国别(地区):
- ES
- 年份:
- 2018
- 代理人:
- 摘要：
- A GlyT1 Inhibitor, Selected [4 - (2 - fluoro - 4 - phenyl - metanosulfonil) piperazin-1-yl] - (2 - isopropoxi - 5 - metanosulfonil phenyl methanone metanosulfonil) - 5 - [2 - (2,2, -2 - trifluoro - 1 - methyl - ethoxy) - phenyl] - [4 - (trifluoromethyl) - 5 - (pyridin-2-yl) piperazin-1-yl] - 4 - isopropoxi methanone - N - methyl - 3 - [4 - (trifluoromethyl) - phenyl) - 1 - piperazin - carbonyl] benzenesulfonamide - [4 - (3 - 5 - fluoro- trifluoromethyl - pyridin-2-yl) piperazin-1-yl] - 5 - [2 - (metanosulfonil - (S) - 2,2,2-trifluoro-1 - ethoxy methyl) phenyl methanone metanosulfonil] - [5 - (2 - (S) - 2.22 - trifluoro - 1 - methyl - (ethoxy) - phenyl] - 3 - trifluoromethyl - 5.7 Dihydro pyrrolo [3,4-b] pyridin-3 (IL - 6) methanone metanosulfonil - [5 - (2 - (S) - 2,2,2-trifluoro-1 - methyl - (ethoxy) - phenyl] 6 - trifluoromethyl - 13 Dihydro pyrrolo [3,4-c] pyridin-2-yl) - methanone or metanosulfonil - [5 - (2 - (S) - 2,2,2-trifluoro-1 - ethoxy methyl) phenyl] - 5 - 6 - methoxy - (trifluoromethyl) - 1,3 - dihydro - isoindol - 2 - il) methanone for use in the Treatment or prevention of hematologic disorders, Selected Sickle Cell Syndrome, thalassemia and iron overload.In particular, for the treatment of hereditary Hemochromatosis.Un inhibidor de Glyt1, seleccionado de [4-(2-fluoro-4-metanosulfonil-fenil)-piperazin-1-il]-(2-isopropoxi-5-metanosulfonil-fenil)-metanona [5-metanosulfonil-2-(2,2,2-trifluoro-1-metil-etoxi)-fenil]-[4-(5-trifluorometil-piridin-2-il)-piperazin-1-il]-metanona 4-isopropoxi-N-metil-3-[4-(4-trifluorometil-fenil)-piperazin-1-carbonil]-bencenosulfonamida [4-(3-fluoro-5-trifluorometil-piridin-2-il)-piperazin-1-il]-[5-metanosulfonil-2-((S)-2,2,2-trifluoro-1-metil-etoxi)-fenil]- metanona [5-metanosulfonil-2-((S)-2,2,2-trifluoro-1-metil-etoxi)-fenil]-(3-trifluorometil-5,7-dihidro-pirrolo[3,4-b]piridin-6-il)- metanona [5-metanosulfonil-2-((S)-2,2,2-trifluoro-1-metil-etoxi)-fenil]-(6-trifluorometil-1,3-dihidro-pirrolo[3,4-c]piridin-2-il)- metanona o [5
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
