INC.;H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE
发明人:
Juan R. Del Valle,Chih-Chi Andrew Hu
申请号：
US16356318
公开号：
US20200024247A1
申请日:
2019.03.18
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Disclosed are XBP-1/IRE-1 inhibitors having formula disclosed herein. Methods of making and using these inhibitors for the treatment of cancer, in particular B cell cancers, are also disclosed. Also disclosed is a genetic XBP-1-knockout cancer mouse model.
