Markus Mandler,Radmila Santic,Harald Weninger,Edith Kopinits
申请号:
US12997673
公开号:
US08409581B2
申请日:
2009.06.12
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to the use of mimotopes in the treatment of β-Amyloidoses including but not limited to Alzheimers disease, whereby said mimotopes are able to induce the in vivo formation of antibodies directed to non truncated Aβ1-40/42, and N-terminally truncated forms AβpE3-40/42, Aβ3-40/42, Aβ11-40/42, AβpE11-40/42 and Aβ14-40/42 without interfering with physiological functions of APP signalling.