Dale G. Swan,Emily R. Rolfes Meyering,Aleksey V. Kurdyumov,Stephen J. Chudzik
申请号：
US12814109
公开号：
US08586731B2
申请日:
2010.06.11
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Hydrophobic α(1→4)glucopyranose polymers with enhanced degradation properties are described. Between the α(1→4)glucopyranose polymeric portion and the hydrophobic portion exists a linker portion having a chemistry that facilitates degradation of the polymer. Diester and carbonate ester linker chemistries are exemplified. Biodegradable matrices can be formed from these polymers, and the matrices can be used for the preparation of implantable and injectable medical devices wherein the matrix is capable of degrading in vivo at an increased rate. Matrices including and capable of releasing a bioactive agent in vivo are also described.
