Marek HONCZARENKO,Shah VAISHALI,Xiaoni LIU,Wendy L. TRIGONA,Rong SHI,Suzanne J. SUCHARD,Karen D. PRICE,Linda M. GUSTAVSON
申请号：
US15118279
公开号：
US20160355596A1
申请日:
2015.03.09
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A method of treating an inflammatory bowel disease is provided. The method comprises administration of an antibody polypeptide that specifically binds a novel epitope of human CD40. The antibody polypeptides do not exhibit CD40 agonist activity. The antibody polypeptides may be fusions of a domain antibody (dAb) comprising a single VL or VH domain and an Fc domain.
