An acyl dipeptide derivative represented by the formula (1) : wherein an acyl group represented by R 1 -CO- is a saturated or unsaturated, straight or branched chain acyl group having 2 - 24 carbon atoms, R 2 and R 3 are each independently a hydrogen atom, an OH group or an OR 5 group, R 5 is a saturated or unsaturated, straight or branched chain hydrocarbon group having 1 - 6 carbon atoms, and R 4 is a hydrogen atom, or a saturated or unsaturated, straight or branched chain hydrocarbon group having 1 - 6 carbon atoms, or a salt thereof has a superior antimicrobial effect, and a composition containing the compound is superior in the sensory feel.