Karl-Uwe Petersen,Michael Ernest Nesheim,Daniel Nesheim,Jonathan Herbert Foley
申请号:
US13377497
公开号:
US20120270789A1
申请日:
2009.06.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to the use of thrombomodulin analogues for the manufacture of a medicament for the treatment of coagulopathy with hyperfibrinolysis, such as haemophilia disorders. These thrombomodulin analogs exhibit at therapeutically effective dosages an antifibrinolytic effect. Novel protein modifications together with methods for their identification are disclosed.